Long-lived chondroprogenitors are generated by fetal-limb Gli1+ cells and are replenished upon mosaic cell-cycle arrest in the cartilage
Xinli Qu, Ehsan Razmara, Chee Ho H’ng, Kailash Kumar Vinu, Luciano Gastón Martelotto, Magnus Zethoven, Fernando Jaime Rossello, Ricky W. Johnstone, Shanika L. Amarasinghe, David Richard Powell, Alberto Roselló‐Díez
The paper identifies Gli1+ cells as fetal precursors of long-lived cartilage progenitors and shows they can compensate for cell-cycle arrest in cartilage.
bioRxiv · Jul 29, 2024 · PreprintDevelopmental Biology