Author

Xuanjia Fan

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:eQTL / molecular QTL mapping· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Michael S. BreeniD· 3 shared Joseph D. BuxbaumiD· 2 shared Winston H. DredgeiD· 2 shared Alexander KolevzoniD· 1 shared Alexey Kozenkov· 1 shared Anna S. TochevaiD· 1 shared Audrey E. ThurmiD· 1 shared Aya OsmaniD· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersDevelopmental Biology

Michael S. BreenORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Expansion of RNA sequence diversity and RNA editing rates throughout human cortical development

Winston H. Dredge, Xuanjia Fan, Laura Gail Sloofman, Lindsay Liang, Enrico Mossotto, Kendall Moore, Sarah Zipkowitz, Minghui Wang, Bin Zhang, Jiebiao Wang, Nenad Šestan, Bernie Devlin, Kathryn Roeder, Stephan Sanders, Joseph D. Buxbaum, Michael S. Breen

The paper examines RNA editing changes during human cortical development, identifying expansion of editing sites and their genetic regulation linked to neurological disorders.

Cell Reports · Nov 1, 2022Peer-reviewedDevelopmental Biology

Large deletions perturb peripheral transcriptomic and metabolomic profiles in Phelan-McDermid syndrome

Michael S. Breen, Xuanjia Fan, Tess Levy, Rebecca M. Pollak, Brett L. Collins, Aya Osman, Anna S. Tocheva, Mustafa Şahin, Elizabeth Berry‐Kravis, Latha Valluripalli Soorya, Audrey E. Thurm, Craig M. Powell, Jonathan Adam Bernstein, Alexander Kolevzon, Joseph D. Buxbaum, , Jennifer M. Phillips

This study identifies molecular differences between PMS patients with small and large deletions, showing reduced cytotoxic cell signatures and sphingolipid metabolism in large deletions.

Human Genetics and Genomics Advances · Sep 26, 2022Peer-reviewedGenetic & Genomic Medicine

Cellular and genetic drivers of RNA editing variation in the human brain

Winston H. Dredge, Junhao Li, Xuanjia Fan, Alexey Kozenkov, Matthew A. Lalli, Shahrukh Khalique, Stella M. Dracheva, Eran A. Mukamel, Michael S. Breen

The paper quantifies RNA editing in human brain cell types, identifies cell-specific editing sites, and discovers cis-editing quantitative trait loci linked to genetic regulation.

Nature Communications · May 30, 2022Peer-reviewedGenetics