Aya Osman

This study shows ketamine reduces heroin-seeking in rats by modulating endogenous opioid and glutamatergic systems, suggesting its potential as an OUD treatment.

This study shows that G-CSF enhances cocaine reward by promoting glutamatergic synaptic remodeling in the nucleus accumbens through calcium-permeable AMPA receptors.

This study shows ECE2 regulates KOR internalization and recycling, with implications for developing therapeutics targeting KOR signaling dysregulation.

The paper shows acetate supplementation improves social deficits and changes gene expression in the prefrontal cortex of Shank3-deficient mice.

This study identifies molecular differences between PMS patients with small and large deletions, showing reduced cytotoxic cell signatures and sphingolipid metabolism in large deletions.

This study shows dietary polyphenols alter behavior, gene expression, and microbiota in response to morphine, with dose-dependent effects.

This study shows that G-CSF enhances cocaine-induced dopamine release in the nucleus accumbens through a direct mechanism, independent of dopamine transporter function.