Author

Sarah Zipkowitz

Icahn School of Medicine at Mount SinaiORCID 0000-0003-1005-331XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Bin ZhangiD· 2 shared Michael S. BreeniD· 2 shared Minghui WangiD· 2 shared Alexander W. CharneyiD· 1 shared Andy Yang· 1 shared Ariela Buxbaum Grice· 1 shared Bernie DevliniD· 1 shared Brendan Sullivan· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Bin ZhangORCID

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2 papers

Recent·Most cited

Divergent landscapes of A-to-I editing in postmortem and living human brain

Miguel Rodríguez de los Santos, Brian Harris Kopell, Ariela Buxbaum Grice, Gauri Ganesh, Andy Yang, Pardis Amini, Lora E. Liharska, Eric Vornholt, John F. Fullard, Pengfei Dong, Eric Y. H. Park, Sarah Zipkowitz, Deepak A. Kaji, Ryan C. Thompson, Donjing Liu, , Michael S. Breen

This study compares A-to-I RNA editing in postmortem and living human brain tissues, revealing significant differences in editing levels and their association with cellular processes and neurological conditions.

Nature Communications · Jun 26, 2024Peer-reviewedGenetic & Genomic Medicine

Expansion of RNA sequence diversity and RNA editing rates throughout human cortical development

Winston H. Dredge, Xuanjia Fan, Laura Gail Sloofman, Lindsay Liang, Enrico Mossotto, Kendall Moore, Sarah Zipkowitz, Minghui Wang, Bin Zhang, Jiebiao Wang, Nenad Šestan, Bernie Devlin, Kathryn Roeder, Stephan Sanders, Joseph D. Buxbaum, Michael S. Breen

The paper examines RNA editing changes during human cortical development, identifying expansion of editing sites and their genetic regulation linked to neurological disorders.

Cell Reports · Nov 1, 2022Peer-reviewedDevelopmental Biology