Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways
Sheng Zhang, Bokyung Kim, Xiaoqing Zhu, Xuehong Gui, Yan Wang, Zhaohui Lan, Preeti Prabhu, Kenneth A. Fond, Aijun Wang, Fuzheng Guo
This study shows that oligodendroglial HIF regulates CNS angiogenesis via VEGF-dependent signaling, independent of Wnt, and reveals a glial cell type-specific HIF-Wnt axis.
Nature Communications · Apr 24, 2020Peer-reviewedNeuroscience