Sheng Zhang

The paper shows how Drosophila larvae influence the lifestyle and pathogenicity of Serratia marcescens at the single-cell level through transcriptomic and metabolic changes.

This study identifies PARP1 as a key driver of oligodendrocyte differentiation and myelination, showing its role in both developmental and remyelination processes in the CNS.

This study shows TCF7l2 promotes oligodendrocyte differentiation by repressing autocrine BMP4 signaling, which is dysregulated in multiple sclerosis.

This study shows HIFα regulates developmental myelination in the CNS independently of autocrine Wnt signaling, identifying a HIF-Sox9 pathway in OPC differentiation.

This study shows that oligodendroglial HIF regulates CNS angiogenesis via VEGF-dependent signaling, independent of Wnt, and reveals a glial cell type-specific HIF-Wnt axis.