Sec14L6 is a PS and PI4P transporter that promotes lipid droplet formation
Tiantian Zhou, Juan Xiong, Xuewen Hu, Yuanjiao Du, Anbing Shi, Weiping Chang, Jichao Qin, Lin Deng, Wei-Ke Ji
This study identifies Sec14L6 as a PS/PI4P transporter essential for lipid droplet formation by interacting with ACSL3 and being recruited to the ER via PGRMC1.
Nature Communications · Nov 26, 2025Peer-reviewedCell Biology