Wei-Ke Ji

This study identifies BLTP1 as a key protein that maintains phosphatidic acid in lipid droplets, preventing overgrowth and ensuring proper LD formation.

This study identifies MOSPD3 as an adaptor that recruits ATG2A to the ER, facilitating autophagy by mediating direct interactions between ATG2A and the ER.

This study identifies Sec14L6 as a PS/PI4P transporter essential for lipid droplet formation by interacting with ACSL3 and being recruited to the ER via PGRMC1.

This study identifies BLTP1 as a mitochondrial phospholipid transporter that prevents lipid overload and apoptosis by exporting phospholipids via FKBP8-tethered ER-mitochondrial contacts.

This study identifies BLTP2's role in lysobisphosphatidic acid synthesis and exosome biogenesis through SCAMP3-dependent ER-MVB contacts, showing its importance in cell proliferation and tumorigenesis.

This study identifies Sec23IP as a VPS13B adaptor that recruits VPS13B to ER exit sites-Golgi interfaces, promoting tubular ERGIC formation and affecting procollagen export, linking it to Cohen syndrome pathogenesis.