Diazo-carboxyl click chemistry enables rapid and sensitive quantification of carboxylic acid metabolites
Cong Li, Kunlun Cheng, Qijin Zhao, Li Jin, Xuelian Wang, Tongling Liufu, Xutong Zhao, Xiaochuan Li, Xiao Dan Wang, Jia Lyu, Dong Huang, Pingping Li, Xiaowei Chen, Zhaoxia Wang, Xinli Hu, , Zhixing Chen
The paper introduces DQmB-HA, a method for sensitive quantification of carboxylic acid metabolites, enabling single-cell analysis and blood sample profiling in mice and humans.
bioRxiv · May 11, 2023 · PreprintSystems Biology