Nuclear cytoophidia assembly represses transcriptional activity to control skeletal development and homeostasis
C. Xu, Z. Wei, L. Lv, X. Dong, W. Xia, J. Xing, H. Liu, X. Zhao, Y. Liu, W. Wang, H. Jiang, Y. Gong, C. Liu, K. Xu, S. Wang, , Z. Hu
This study identifies nuclear cytoophidia as regulators of Impdh2 transcriptional activity, impacting skeletal development and homeostasis through effects on endochondral ossification and osteoclast function.
bioRxiv · Dec 10, 2023 · PreprintCell Biology