Author

Y. Bhoobalan-Chitty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

X. Peng· 3 shared A. Salegi-Diez· 1 shared D. Mayo-Munoz· 1 shared D. Stickel· 1 shared H. Yan· 1 shared K. Baadsgaard· 1 shared L. Deng· 1 shared L. H. Hansen· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersMicrobiology

X. Peng

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Multilayered interaction between CRISPR-Cas subtype I-A and adjacently encoded Acrs of virus SIRV2

Y. Bhoobalan-Chitty, N. Dwiputra, D. Mayo-Munoz, K. Baadsgaard, M. R. K. S. Detlefsen, X. Peng

The paper investigates the interaction between CRISPR-Cas subtype I-A and two adjacent Acrs in SIRV2, showing how they modulate viral infectivity and host immunity.

bioRxiv · Apr 2, 2024 · PreprintMicrobiology

To be or not to be an anti-CRISPR: AcrIII-1 and the importance of working with native biological systems

L. Martinez-Alvarez, D. Stickel, A. Salegi-Diez, Y. Bhoobalan-Chitty, X. Peng

This study shows that SIRV2 gp37 lacks anti-CRISPR activity in native infections but provides a replicative advantage through host protein interaction.

bioRxiv · Jan 10, 2023 · PreprintMicrobiology

Replication protein Rep provides selective advantage to viruses in the presence of CRISPR-Cas immunity

W. Zhang, Y. Bhoobalan-Chitty, X. Zhai, H. Yan, L. H. Hansen, L. Deng, X. Peng

This study shows that the viral replication protein Rep provides a selective advantage in the presence of CRISPR-Cas immunity by enhancing viral replication efficiency and outcompeting CRISPR-null variants.

bioRxiv · Nov 18, 2021Microbiology