Author

Y. Bloch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:plant (other)· 2 Assay:protein structure· 2 Research Focus:protein structure prediction· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

S. N. Savvides· 3 shared A. C. Papageorgiou· 1 shared C. Gabay· 1 shared D. Clancy· 1 shared D. Eeckhout· 1 shared D. Van Damme· 1 shared E. J. Van Damme· 1 shared G. De Jaeger· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBiochemistry

S. N. Savvides

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3 papers

Recent·Most cited

The crystal structure of Nictaba reveals its carbohydrate-binding properties and a new lectin dimerization mode

Y. Bloch, V. J. Osterne, S. N. Savvides, E. J. Van Damme

This paper reports the crystal structure of Nictaba, revealing its carbohydrate-binding properties and a novel lectin dimerization mode.

bioRxiv · May 6, 2024Biochemistry

Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein (IL-18BP) in inflammation and tumor immunity

S. Detry, J. Andries, Y. Bloch, C. Gabay, D. Clancy, S. N. Savvides

This paper determines the crystal structure of the human IL-18:IL-18BP complex, revealing the molecular mechanism of IL-18 sequestration and identifying a higher-order 2:2 assembly with enhanced activity restraint.

bioRxiv · Feb 10, 2022Immunology

Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding.

K. Yperman, A. C. Papageorgiou, R. Merceron, S. De Munck, Y. Bloch, D. Eeckhout, P. Tack, T. Evangelidis, J. Van Leene, L. Vincze, P. Vandenabeele, M. Potocky, G. De Jaeger, S. N. Savvides, K. Tripsianes, , D. Van Damme

This study identifies distinct lipid and protein binding roles of EH domains in the TPLATE complex, revealing their functional contributions to plant clathrin-mediated endocytosis.

bioRxiv · May 29, 2020Plant Biology