Author

P. Vandenabeele

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

E. Dierick· 2 shared J. Maelfait· 2 shared R. de Reuver· 2 shared A. Botzki· 1 shared A. C. Papageorgiou· 1 shared A. Goncalves· 1 shared B. Gilbert· 1 shared B. Lambrecht· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

E. Dierick

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Type 1 immunity enables neonatal thymic ILC1 production

P. Tougaard, M. R. Perez, W. Steels, J. Huysentruyt, B. Verstraeten, J. Vetters, T. Divert, A. Goncalves, R. Roelandt, N. Takahashi, S. Janssens, T. B. Buus, T. Taghon, G. Leclercq, P. Vandenabeele

The paper shows type 1 immunity drives thymic production and peripheral migration of ILC1s in neonates.

Science Advances · Jan 19, 2024Peer-reviewedImmunology

ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation.

R. de Reuver, E. Dierick, B. Wiernicki, K. Staes, L. Seys, E. De Meester, T. Muyldermans, A. Botzki, B. Lambrecht, F. Van Nieuwerburgh, P. Vandenabeele, J. Maelfait

This study shows that ADAR1's interaction with Z-RNA reduces A-to-I editing of self-dsRNA, leading to MDA5-dependent immune activation and AGS in mutant cells and mice.

bioRxiv · Dec 4, 2020Immunology

Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding.

K. Yperman, A. C. Papageorgiou, R. Merceron, S. De Munck, Y. Bloch, D. Eeckhout, P. Tack, T. Evangelidis, J. Van Leene, L. Vincze, P. Vandenabeele, M. Potocky, G. De Jaeger, S. N. Savvides, K. Tripsianes, , D. Van Damme

This study identifies distinct lipid and protein binding roles of EH domains in the TPLATE complex, revealing their functional contributions to plant clathrin-mediated endocytosis.

bioRxiv · May 29, 2020Plant Biology

Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation

M. Devos, G. Tanghe, B. Gilbert, E. Dierick, M. Verheirstraeten, J. Nemegeer, R. de Reuver, S. Lefebvre, J. De Munck, J. Rehwinkel, P. Vandenabeele, W. Declercq, J. Maelfait

The paper shows that ZBP1 sensing of endogenous nucleic acids causes necroptosis and skin inflammation in RIPK1-deficient keratinocytes, linked to IL-17 immune responses.

bioRxiv · Mar 25, 2020Immunology