MitoToxy Assay: a novel cell-based method for the assessment of metabolic toxicity in a multiwell plate format using a lactate FRET nanosensor, Laconic
Y. Contreras, S. Ceballo, R. Arce, P. Sandoval, K. Alegria, F. Barros, A. A. San Martin
The paper introduces a cell-based assay using a lactate FRET nanosensor to detect mitochondrial toxicity in drug development with high sensitivity and throughput.
bioRxiv · Mar 20, 2019Pharmacology & Toxicology