Chk2 sustains PLK1 activity in mitosis to ensure proper chromosome segregation
E. M. Black, C. A. Ramirez Parrado, I. Trier, W. V. Li, Y. K. Joo, J. Pichurin, Y. Liu, L. Kabeche
This study identifies Chk2 as a regulator of PLK1 activity during mitosis, showing its role in preventing chromosome segregation errors and genome instability.
bioRxiv · Mar 8, 2024 · PreprintCell Biology