Author

L. Kabeche

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Assay:electrophysiology· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

I. Trier· 3 shared Y. K. Joo· 2 shared A. Bali· 1 shared A. L. Zhang· 1 shared C. A. Ramirez Parrado· 1 shared C. E. Paulsen· 1 shared E. Black· 1 shared E. M. Black· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCell Biology

I. Trier

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Chk2 sustains PLK1 activity in mitosis to ensure proper chromosome segregation

E. M. Black, C. A. Ramirez Parrado, I. Trier, W. V. Li, Y. K. Joo, J. Pichurin, Y. Liu, L. Kabeche

This study identifies Chk2 as a regulator of PLK1 activity during mitosis, showing its role in preventing chromosome segregation errors and genome instability.

bioRxiv · Mar 8, 2024 · PreprintCell Biology

ATR protects centromere identity by promoting DAXX association with PML nuclear bodies

I. Trier, Y. K. Joo, E. Black, L. Kabeche

This study shows ATR protects CENP-A occupancy at centromeres by regulating DAXX association with PML nuclear bodies, maintaining genome stability.

bioRxiv · Sep 26, 2022Cell Biology

Molecular Mechanism of Hyperactivation Conferred by a Truncated TRPA1 Disease Mutant Suggests New Gating Insights

A. Bali, S. P. Schaefer, I. Trier, A. L. Zhang, L. Kabeche, C. E. Paulsen

This paper investigates the R919* TRPA1 mutant, showing it is functionally inactive alone but enhances agonist sensitivity when co-expressed with wild-type TRPA1, revealing a novel mechanism of channel hyperactivation.

bioRxiv · Jan 5, 2022 · PreprintBiochemistry