Co-inhibition of BCL-XL and MCL-1 with BCL-2 selective inhibitors A1331852 and S63845 enhances cytotoxicity of cervical cancer cell lines
S. F. Abdul Rahman, K. Muniandy, Y. K. Soo, E. Y. H. Tiew, K. X. Tan, T. E. Bates, N. Mohana Kumaran
This study shows that combining BCL-XL and MCL-1 inhibitors A1331852 and S63845 significantly enhances cytotoxicity in cervical cancer cell lines compared to single-agent treatments.
bioRxiv · Oct 30, 2019Cancer Biology