Author

S. F. Abdul Rahman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

N. Mohana Kumaran· 3 shared K.-W. Lo· 2 shared A. Azlan· 1 shared D. Singh· 1 shared E. Y. H. Tiew· 1 shared G. Azzam· 1 shared G. Domnic· 1 shared K. Muniandy· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

N. Mohana Kumaran

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Dual inhibition of anti-apoptotic proteins BCL-XL and MCL-1 enhances cytotoxicity of Nasopharyngeal carcinoma cells.

S. F. Abdul Rahman, A. Azlan, K.-W. Lo, G. Azzam, N. Mohana Kumaran

This study identifies MCL-1 and BCL-XL as critical for NPC cell survival and shows that their dual inhibition enhances cytotoxicity in NPC cells.

bioRxiv · Jul 7, 2021Cancer Biology

Combinations of Indole based alkaloids from Mitragyna speciosa (Kratom) and cisplatin inhibit cell proliferation and migration of Nasopharyngeal carcinoma cell lines

G. Domnic, S. F. Abdul Rahman, N. J. Y. Chear, S. Ramanathan, K.-W. Lo, D. Singh, N. Mohana Kumaran

This study investigates the combination of indole-based alkaloids from kratom with cisplatin to inhibit nasopharyngeal carcinoma cell proliferation and migration.

bioRxiv · Dec 18, 2020 · PreprintCancer Biology

Co-inhibition of BCL-XL and MCL-1 with BCL-2 selective inhibitors A1331852 and S63845 enhances cytotoxicity of cervical cancer cell lines

S. F. Abdul Rahman, K. Muniandy, Y. K. Soo, E. Y. H. Tiew, K. X. Tan, T. E. Bates, N. Mohana Kumaran

This study shows that combining BCL-XL and MCL-1 inhibitors A1331852 and S63845 significantly enhances cytotoxicity in cervical cancer cell lines compared to single-agent treatments.

bioRxiv · Oct 30, 2019Cancer Biology