Author

N. Mohana Kumaran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

K.-W. Lo· 3 shared S. F. Abdul Rahman· 3 shared A. Azlan· 1 shared A. S.-B. Khoo· 1 shared B. S. X. Lian· 1 shared D. Singh· 1 shared E. Y. H. Tiew· 1 shared G. Azzam· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersCancer Biology

K.-W. Lo

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Author profile →

4 papers

Recent·Most cited

Cancer BiologybioRxivJul 7, 2021

Dual inhibition of anti-apoptotic proteins BCL-XL and MCL-1 enhances cytotoxicity of Nasopharyngeal carcinoma cells.

S. F. Abdul Rahman, A. Azlan, K.-W. Lo…·N. Mohana Kumaran

This study identifies MCL-1 and BCL-XL as critical for NPC cell survival and shows that their dual inhibition enhances cytotoxicity in NPC cells.

DOI 10.1007/s12672-022-00470-9

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintDec 18, 2020

Combinations of Indole based alkaloids from Mitragyna speciosa (Kratom) and cisplatin inhibit cell proliferation and migration of Nasopharyngeal carcinoma cell lines

G. Domnic, S. F. Abdul Rahman, N. J. Y. Chear…·N. Mohana Kumaran

This study investigates the combination of indole-based alkaloids from kratom with cisplatin to inhibit nasopharyngeal carcinoma cell proliferation and migration.

DOI 10.1101/2020.12.18.423377

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivOct 30, 2019

Co-inhibition of BCL-XL and MCL-1 with BCL-2 selective inhibitors A1331852 and S63845 enhances cytotoxicity of cervical cancer cell lines

S. F. Abdul Rahman, K. Muniandy, Y. K. Soo…·N. Mohana Kumaran

This study shows that combining BCL-XL and MCL-1 inhibitors A1331852 and S63845 significantly enhances cytotoxicity in cervical cancer cell lines compared to single-agent treatments.

DOI 10.1016/j.bbrep.2020.100756

humanexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivNov 16, 2018

Single Agent and Synergistic Activity of Maritoclax with ABT-263 in Nasopharyngeal Carcinoma (NPC) Cell Lines

B. S. X. Lian, K.-W. Lo, A. S.-B. Khoo, N. Mohana Kumaran

This study evaluates Maritoclax and its combination with ABT-263 in NPC cell lines, showing single-agent and synergistic effects on cell proliferation and resistance in 3D spheroids.

DOI 10.21315/tlsr2020.31.3.1

humanexperimental assay

𝕏 PostBluesky