Author

Y. L. Luo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

W. Jiang· 2 shared A. Bhatt· 1 shared A. L. Harris· 1 shared C. I. Fernandez· 1 shared C. Wen· 1 shared D. Kumar· 1 shared H. Zhang· 1 shared J. E. Contreras· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiophysics

W. Jiang

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3 papers

Recent·Most cited

Optimizing Coarse-Grained Models for Large-Scale Membrane Protein Simulation

C. Wen, Y. L. Luo, J. Madsen

This paper optimizes a coarse-grained lipid model for large-scale membrane protein simulations and demonstrates its application to study PIEZO-induced membrane deformation.

bioRxiv · May 13, 2024Biophysics

Large-pore connexin hemichannels function as molecule transporters independently of ion conduction

P. S. Gaete, D. Kumar, C. I. Fernandez, J. M. Valdez-Capuccino, A. Bhatt, W. Jiang, Y. Lin, Y. Liu, A. L. Harris, Y. L. Luo, J. E. Contreras

The paper shows that connexin hemichannels can transport molecules independently of ion conduction, challenging the conventional view of their function.

bioRxiv · Feb 20, 2024 · PreprintBiophysics

A Piezo1 open state reveals a multi-fenestrated ion permeation pathway

W. Jiang, J. S. Del Rosario, W. M. Botello-Smith, S. Zhao, Y.-C. Lin, H. Zhang, J. J. Lacroix, T. Rohacs, Y. L. Luo

The paper uses molecular dynamics simulations to study Piezo1 channel opening and identifies a multi-fenestrated ion permeation pathway.

Communications Biology · Jan 19, 2021Peer-reviewedBiophysics