Author

J. Madsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Biophysics· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:DNA methylation· 2 Organism:bacteria (other)· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

A. A. Teklu· 1 shared A. D. Postle· 1 shared A. Dunn· 1 shared A. Lin· 1 shared A. Paoli· 1 shared B. Fink· 1 shared B. Flinders· 1 shared B. Kraigher· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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1 shared paperPhysiology

A. A. Teklu

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Author profile →

5 papers

Recent·Most cited

Optimizing Coarse-Grained Models for Large-Scale Membrane Protein Simulation

C. Wen, Y. L. Luo, J. Madsen

This paper optimizes a coarse-grained lipid model for large-scale membrane protein simulations and demonstrates its application to study PIEZO-induced membrane deformation.

bioRxiv · May 13, 2024Biophysics

Ketones facilitate transcriptional resolution of secondary DNA structures in premature aging

M. A. Petr, L. M. Carmona-Marin, T. Tulika, S. Kristensen, S. Reves, D. Bakula, G. Keijzers, B. Osborne, S. J. Mitchell, S. Hamilton, J. Kato, I. Alfaras, A. A. Teklu, I. Heckenbach, J. Madsen, , M. Scheibye-Knudsen

This study shows that ketones like beta-hydroxybutyrate reduce premature aging features in Cockayne syndrome models by enhancing transcriptional readthrough of DNA secondary structures through histone acetylation.

bioRxiv · Mar 8, 2022 · PreprintPhysiology

Kin discrimination promotes horizontal gene transfer between unrelated strains in Bacillus subtilis

P. Stefanic, K. Belcijan, B. Kraigher, R. Kostanjsek, J. Nesme, j. Madsen, J. Kovac, S. J. Sorensen, M. Vos, I. Mandic-Mulec

This study shows that kin discrimination in B. subtilis promotes horizontal gene transfer between distantly related strains by inducing competence in recipients through a stress response.

bioRxiv · Mar 4, 2021 · PreprintMicrobiology

Mass spectrometry imaging of phosphatidylcholine metabolism in lungs administered with therapeutic surfactants and isotopic tracers

S. R. Ellis, E. Halll, M. Panchal, B. Flinders, J. Madsen, G. Koster, R. M. A. Heeren, H. W. Clark, A. D. Postle

The paper uses mass spectrometry imaging with isotopic tracers to visualize phosphatidylcholine metabolism in mouse lungs, revealing metabolic processes and acyl chain remodeling.

bioRxiv · Oct 7, 2020Biochemistry

Biomimetic sponges improve muscle structure and function following volumetric muscle loss

G. Haas, A. Dunn, J. Madsen, P. Genovese, A. Lin, H. Chauvin, J. Au, A. Paoli, K. Garg

This study shows that biomimetic sponges improve muscle structure and function in a rodent model of volumetric muscle loss by enhancing myofiber regeneration and reducing fibrosis.

bioRxiv · May 20, 2020Bioengineering