Galectin-1-deficient mice are protected against Trypanosoma cruzi infection through altered neutrophil migration and production of reactive oxygen species and nitric oxide
T. B. Riul, H. Sales-Campos, D. d. S. Lima-Junior, A. E. C. Seixas Azzolini, C. R. d. B. Cardoso, S. R. Stowell, R. D. Cummings, Y. M. L. Valim, M. D. Baruffi
This study shows that Galectin-1 deficiency in mice reduces T. cruzi parasitemia and increases survival by enhancing neutrophil migration and reactive oxygen species/nitric oxide production.
bioRxiv · Sep 11, 2020 · PreprintImmunology