Author

Y. N. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Nagler· 2 shared A. Arbiv· 1 shared A. Borkhard· 1 shared A. Hendel· 1 shared A. Lev· 1 shared A. M. Savino· 1 shared A. Rein Gil· 1 shared C. James· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioengineering

A. Nagler

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Multiplex HDR for Disease and Correction Modeling of SCID by CRISPR Genome Editing in Human HSPCs

O. Iancu, D. Allen, O. Knop, Y. Zehavi, D. Breier, A. Arbiv, A. Lev, Y. N. Lee, K. Beider, A. Nagler, R. Somech, A. Hendel

This paper models SCID and tests gene correction in human HSPCs using CRISPR-Cas9 and multiplexed HDR, showing successful T-cell development from corrected cells.

bioRxiv · Oct 7, 2022Bioengineering

An instructive role for IL7RA in the development of human B-cell precursor leukemia.

I. Geron, A. M. Savino, N. Tal, H. Fishman, J. Brown, V. Turati, C. James, J. Sarno, Y. N. Lee, A. Rein Gil, Y. Birger, I. Muler, M. Hameiri-Grossman, V. Marcu-Malina, O. Parnas, , S. Izraeli

This study shows that aberrant IL7RA signaling in human hematopoietic progenitors leads to B-cell differentiation arrest and Ph-like BCP-ALL development in mice.

bioRxiv · Jan 27, 2020 · PreprintCancer Biology