Cell BiologybioRxiv
mTORC1 activity is supported by spatial association with focal adhesions
Y. Rabanal-Ruiz, A. Byron, A. Wirth…·V. I. Korolchuk
This study shows that mTORC1 activation by growth factors and amino acids requires its spatial association with focal adhesions, independent of lysosomal distribution.
DOI 10.1083/jcb.202004010