Author

Y. Saiman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1

Frequent Co-Authors

B. A. Garcia· 1 shared B. Ogretmen· 1 shared C. D. Allis· 1 shared C. Lin· 1 shared C. Petucci· 1 shared D. Buyco· 1 shared E. S. Friedman· 1 shared E. Scorletti· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

B. A. Garcia

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2 papers

Recent·Most cited

Ceramide synthase 6 (CerS6) promotes alcohol-induced fatty liver by promoting metabolic dysfunction and upregulating lipid droplet-associated proteins

S. Jeon, E. Scorletti, D. Buyco, C. Lin, Y. Saiman, J. Martin, R. Hooks, B. Ogretmen, J. Argemi, L. Melo, R. Bataller, R. M. Carr

This study shows that deleting CerS6 reduces alcohol-induced fatty liver and improves glucose homeostasis in mice, and links CerS6 expression to ALD progression in humans.

bioRxiv · Nov 3, 2022 · PreprintPathology

Stable Isotope Tracing In Vivo Reveals A Metabolic Bridge Linking The Microbiota To Host Histone Acetylation

P. J. Lund, L. A. Gates, M. Leboeuf, S. A. Smith, L. Chau, E. S. Friedman, M. Lopes, Y. Saiman, M. S. Kim, C. Petucci, C. D. Allis, G. D. Wu, B. A. Garcia

This study uses stable isotope tracing to show that gut microbiota supply carbon for host histone acetylation, linking microbial metabolism to host epigenetic regulation.

bioRxiv · Jul 5, 2021Biochemistry