Genome-Scale CRISPR Screening reveals novel factors regulating Wnt-dependent regeneration of mouse gastric organoids
K. Murakami, Y. Terakado, K. Siato, Y. Jomen, H. Takeda, M. Oshima, N. Barker
The paper uses CRISPR screening to identify novel factors regulating Wnt-dependent regeneration of mouse gastric organoids, finding that Alk, Bclaf3, and Prkra suppress Wnt-driven self-renewal.
bioRxiv · Jul 17, 2020 · PreprintCell Biology