Author

N. Barker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. D. Gracz· 1 shared A. Gleizes· 1 shared A. T. Papadopulos· 1 shared A. Tsankov· 1 shared B. Giotti· 1 shared C. Company· 1 shared D. Demircioglu· 1 shared D. Hasson· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCell Biology

A. D. Gracz

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Lgr5+ intestinal stem cells are required for organoid survival after genotoxic injury

J. Lee, A. Gleizes, F. Takaesu, T. Hailstock, S. F. Webster, N. Barker, A. D. Gracz

This study shows that Lgr5+ intestinal stem cells are necessary for organoid survival after genotoxic injury, despite fISC gene activation occurring at both low and high doses of doxorubicin.

bioRxiv · Apr 8, 2024Cell Biology

A Mutation-driven oncofetal regression fuels phenotypic plasticity in colorectal cancer

S. Mzoughi, M. Schwarz, X. Wang, D. Demircioglu, G. Ulukaya, K. Mohammed, F. Di Tullio, C. Company, Y. Dramaretska, M. Leushacke, B. Giotti, T. Lannagan, D. Lozano-Ojalvo, D. Hasson, A. Tsankov, , E. Guccione

This study identifies an oncofetal cell state that contributes to resistance in colorectal cancer and shows that targeting both this state and LGR5+ CSCs is needed for effective treatment.

bioRxiv · Dec 10, 2023Cancer Biology

Hybridisation and chloroplast capture between ancient Themeda triandra ecotypes in Australia

L. T. Dunning, J. K. Oloffson, A. T. Papadopulos, P. C. Baleeiro, S. Ntshangase, N. Barker, R. W. Jobson

This study uses whole genome sequencing to analyze hybridization and chloroplast capture between ecotypes of Themeda triandra in Australia, revealing gene flow and adaptive introgression.

bioRxiv · Oct 21, 2021 · PreprintEvolutionary Biology

Genome-Scale CRISPR Screening reveals novel factors regulating Wnt-dependent regeneration of mouse gastric organoids

K. Murakami, Y. Terakado, K. Siato, Y. Jomen, H. Takeda, M. Oshima, N. Barker

The paper uses CRISPR screening to identify novel factors regulating Wnt-dependent regeneration of mouse gastric organoids, finding that Alk, Bclaf3, and Prkra suppress Wnt-driven self-renewal.

bioRxiv · Jul 17, 2020 · PreprintCell Biology