Activation of Complement by Human Fibrin Clots: involvement of C1q and factor H
Y.-H. Kang, P. Varghese, K. Pondman, U. Kishore, R. Sim
This study shows fibrin clots activate the classical complement pathway, which is regulated by factor H, through covalent binding mediated by FXIIIa.
bioRxiv · Oct 19, 2023 · PreprintImmunology