High-altitude hypoxia exposure inhibits erythrophagocytosis by inducing macrophage ferroptosis in the spleen
W.-p. Yang, M.-q. Li, J. Ding, J.-y. Li, G. Wu, B. Liu, Y.-q. Gao, G. Wang, Q.-q. Luo
This study shows that high-altitude hypoxia induces splenic macrophage ferroptosis, reducing erythrophagocytosis and contributing to high-altitude polycythemia.
bioRxiv · Mar 23, 2023Physiology