Author

Y.-Y. Lu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

C. Beissel· 1 shared C. L. Lee· 1 shared C. Li· 1 shared C. Liu· 1 shared C.-T. Yen· 1 shared C.-Y. Huang· 1 shared D.-M. Niu· 1 shared F. Yang· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCell Biology

C. Beissel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Challenging the Conventional Treatment Initiation Paradigm: Early Detection of Irreversible Cellular Damage in Cardiac Biopsies of Fabry Disease Before the Formation of Gb3 Inclusion Bodies

C. L. Lee, P.-S. Chen, Y.-Y. Lu, Y.-T. Chiang, C.-T. Yen, C.-Y. Huang, Y.-F. Cheng, H.-Y. Lin, Y.-R. Chen, D.-M. Niu

This study shows that cardiac biopsies from Fabry disease patients exhibit significant cellular stress and irreversible damage before Gb3 inclusion bodies form, suggesting earlier treatment initiation is needed.

bioRxiv · Jun 28, 2024 · PreprintPathology

Function-associated scRNA-seq on single lung cancer organoids unravels the immune landscape of tumor parenchyma

C. Liu, K. Li, X. Sui, T. Zhao, T. Zhang, Z. Chen, H. Wu, C. Li, H. Li, F. Yang, Z. Liu, Y.-Y. Lu, J. Wang, X. Chen, P. Liu

The paper uses single-cell RNA sequencing on lung cancer organoids to study the tumor immune microenvironment and identifies key genes and T cell activity factors related to immunotherapy response.

bioRxiv · Dec 11, 2023 · PreprintCancer Biology

A potential function for the helicase Dbp5 in cytoplasmic quality control

L. Querl, Y.-Y. Lu, C. Beissel, H. Krebber

This study investigates Dbp5's role in cytoplasmic mRNA quality control, showing its involvement in NMD and potential delivery of Dom34 to NGD and NSD substrates.

bioRxiv · Nov 11, 2022 · PreprintCell Biology