Assembling Ruthenium Complexes to Form Ruthenosome Unleashing Ferritinophagy-mediated Tumor Suppression
Caiting Meng, Shuaijun Li, Yana Ma, Hongwen Yu, Jiaqi Song, Junchao Zhi, Bin Zhu, Liang Shao, Xinling Liu, Lulu Yang, Mingzhen Zhang, Ye Zhang, Guanying Li
This paper introduces ruthenosomes, engineered ruthenium complexes that induce ferroptosis by enhancing ROS levels and activating ferritinophagy, effectively suppressing colorectal tumor growth.
ACS Nano · Mar 5, 2025Peer-reviewedBiochemistry