Ye Zhang

This study shows that terminal modifications of integrin ligands can reprogram their supramolecular organization and function, affecting cell migration without altering the sequence.

This study shows that integrin-mediated mechanotransduction through supramolecular ligand clustering limits mitochondrial respiratory capacity, thereby suppressing cancer cell motility and tumor growth.

This paper develops ECM-mimetic cellular patches that reprogram mesenchymal stem cells into neurons through mechanical remodeling without genetic or chemical induction.

This paper introduces ruthenosomes, engineered ruthenium complexes that induce ferroptosis by enhancing ROS levels and activating ferritinophagy, effectively suppressing colorectal tumor growth.