Large-scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines
Wei Zhao, Jun Li, Mei-Ju M. Chen, Yikai Luo, Zhenlin Ju, Nicole K. Nesser, Katie Johnson-Camacho, Christopher T. Boniface, Yancey Lawrence, Nupur T. Pande, Michael A. Davies, Meenhard Herlyn, Taru E. Muranen, Ioannis K. Zervantonakis, Erika von Euw, , Han Liang
The paper compiles protein response data from cancer cell lines to drug perturbations, showing improved drug sensitivity prediction and building a protein-drug connectivity map with an accessible data portal.
Cancer Cell · Nov 5, 2020Peer-reviewedSystems Biology