Author

Ye Wang

Columbia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

Click to filter author papers

Bioinformatics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:variant effect prediction· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Abigail Hunter· 1 shared Andrew J. SaykiniD· 1 shared Bing YaoiD· 1 shared Brianna LaVioletteiD· 1 shared Chaolin ZhangiD· 1 shared Chencheng Xu· 1 shared Congsheng Cheng· 1 shared Dinesh Hirenallur Shanthapa· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMolecular Biology

Abigail Hunter

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Reference-informed prediction of alternative splicing and splicing-altering mutations from sequences

Chencheng Xu, Suying Bao, Ye Wang, Wenxing Li, Hao Chen, Yufeng Shen, Tao Jiang, Chaolin Zhang

DeltaSplice predicts splicing-altering mutations and alternative splicing from genomic sequences, outperforming existing methods and identifying disease-related variants in neurodevelopmental disorders.

Genome Research · Jul 1, 2024Peer-reviewedBioinformatics

Targeting ABCB4 using mRNA-LNP for the treatment of rare liver diseases

Mohammed Alsuraih, Brianna LaViolette, Guan-Yu Lin, Ramesh C. Kovi, Natalie A. Daurio, Congsheng Cheng, Youngwook Ahn, Zhihua Jiang, Roberto Ortiz, Shangzhong Li, Yuxing Cheng, Ye Wang, Xiaoyu Fan, Jessica Haskins, Xiuhua Sun, , Shian-Huey Chiang

This study demonstrates that systemic delivery of hABCB4 mRNA LNPs ameliorates liver fibrosis and bile phosphatidylcholine levels in a PFIC3 mouse model.

bioRxiv · Apr 11, 2023 · PreprintMolecular Biology

WEVar: a novel statistical learning framework for predicting noncoding regulatory variants

Ye Wang, Yuchao Jiang, Bing Yao, Kun Huang, Yunlong Liu, Yue Wang, Xiao Qin, Andrew J. Saykin, Li Chen

WEVar integrates functional scores from multiple methods to predict noncoding regulatory variants, outperforming existing approaches in simulation and empirical studies.

Briefings in Bioinformatics · Apr 23, 2021Peer-reviewedBioinformatics