The pioneer transcription factor ELF2 remodels the nucleosome near transcription start sites
Tianyi Xiao, Caillan Crowe‐McAuliffe, Moritz Ochmann, Yepeng Du, Tianyun Hou, Yinan Chen, Fangjie Zhu, Fatemeh S. Seyednasrollah, Maria Osmala, Sakari Vanharanta, Ekaterina Yu. Morgunova, Patrick Cramer, Connor Rogerson, Christian Dienemann, Jussi Taipale
This study reveals how ELF2, a pioneer transcription factor, remodels nucleosomes near transcription start sites by unwrapping DNA and exposing chromatin, facilitating transcription initiation.
bioRxiv · May 24, 2024 · PreprintBiochemistry