Author

Moritz Ochmann

Max Planck Institute for Multidisciplinary SciencesORCID 0000-0003-3833-5650Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:structural biology· 2 Assay:ChIP-seq· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Patrick CrameriD· 3 shared Christian DienemanniD· 2 shared Aiturgan ZheenbekovaiD· 1 shared Caillan Crowe‐McAuliffeiD· 1 shared Christiane Oberthuer· 1 shared Connor RogersoniD· 1 shared Ekaterina Yu. MorgunovaiD· 1 shared Fangjie ZhuiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersBiochemistry

Patrick CramerORCID

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3 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedOct 29, 2025

Molecular mechanism of co-transcriptional H3K36 methylation by SETD2

James L. Walshe, Moritz Ochmann, Ute Neef…·Patrick Cramer

This study reveals a three-step mechanism of co-transcriptional H3K36 methylation by SETD2 through cryo-EM structures and functional analysis.

13 citations

structural biologyexperimental assay

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BiochemistrybioRxivPreprintMay 24, 2024

The pioneer transcription factor ELF2 remodels the nucleosome near transcription start sites

Tianyi Xiao, Caillan Crowe‐McAuliffe, Moritz Ochmann…·Jussi Taipale

This study reveals how ELF2, a pioneer transcription factor, remodels nucleosomes near transcription start sites by unwrapping DNA and exposing chromatin, facilitating transcription initiation.

2 citations

structural biologyexperimental assay

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Molecular BiologyeLifePeer-reviewedJun 16, 2020

Nucleosome-CHD4 chromatin remodeller structure explains human disease mutations

Lucas Farnung, Moritz Ochmann, Patrick Cramer

The paper reports the cryo-EM structure of CHD4 bound to a nucleosome, explaining how mutations in CHD4 contribute to cancer and intellectual disability.

95 citationstop 4%

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