Author

Yi-Shiuan Tseng

National Cheng Kung University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:machine learning (classical)· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

Lauren HongiD· 1 shared Matthew P. DeLisaiD· 1 shared Po‐Han CheniD· 1 shared Pranam ChatterjeeiD· 1 shared Sophia VincoffiD· 1 shared Tai-Chen Ho· 1 shared Thomas Connor Donahue· 1 shared Tong CheniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperSynthetic Biology

Lauren HongORCID

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1 paper

Recent·Most cited

PepRePs: Peptide-Retargeted Phosphatases Designed with Generative Language Models

Lauren Hong, Tai-Chen Ho, Yi-Shiuan Tseng, Sophia Vincoff, Tong Chen, Thomas Connor Donahue, Matthew P. DeLisa, Po‐Han Chen, Pranam Chatterjee

This paper introduces PepRePs, a system using peptide-retargeted phosphatases to selectively manipulate protein phosphorylation, showing reduced phosphorylation and downstream effects on cellular processes.

bioRxiv · Oct 6, 2026 · PreprintSynthetic Biology