Ying Chu

Occurrence of Carbapenem-resistant Enterobacterales in swine wastewater in Shandong Province, China

This study identifies carbapenemase-producing E. coli in swine wastewater in Shandong, China, highlighting their multidrug resistance and genetic diversity.

Conditioned pain modulation recruits the descending pain modulatory system to inhibit spinal activity

This study uses fMRI to show that conditioned pain modulation involves reduced spinal activity and increased descending pain modulation during pain suppression in humans.

Ventral premotor cortex influences spinal cord activation during force generation

Conditioned pain modulation of pressure pain is associated with reduced activation in the parietal operculum and posterior insula

The paper investigates neural correlates of conditioned pain modulation (CPM) using fMRI and finds reduced activation in parietal operculum and posterior insula associated with CPM.

A single TRPV1 amino acid controls species sensitivity to capsaicin

The paper identifies a single amino acid substitution in TRPV1 that determines species sensitivity to capsaicin between birds and mammals.

It takes two vanilloid ligand bindings per channel to transduce painful capsaicin stimuli

The paper shows that two vanilloid ligand bindings per TRPV1 channel are sufficient for maximal pain signaling, revealing how TRPV1 integrates pain signals from multiple stimuli.