A single TRPV1 amino acid controls species sensitivity to capsaicin
Ying Chu, Bruce E. Cohen, Huai-hu Chuang
The paper identifies a single amino acid substitution in TRPV1 that determines species sensitivity to capsaicin between birds and mammals.
Author
Institute of Molecular Biology, Academia Sinica
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
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Ying Chu, Bruce E. Cohen, Huai-hu Chuang
The paper identifies a single amino acid substitution in TRPV1 that determines species sensitivity to capsaicin between birds and mammals.
Mingyi Zhou, Ya-Yu Hu, Huai-hu Chuang
The paper investigates how G protein-coupled receptor distribution affects signal transmission efficacy by analyzing the kinetics of calcium-induced chloride currents in Xenopus oocytes.
Tingyi “Leo” Liu, Ying Chu, Hao‐Ruei Mei…·Huai-hu Chuang
The paper shows that two vanilloid ligand bindings per TRPV1 channel are sufficient for maximal pain signaling, revealing how TRPV1 integrates pain signals from multiple stimuli.