Rational Design of 5' UTRs for Optimized mRNA Expression and Cost-Effective, Rapid Analysis of Capped mRNA
Yuan Fang, Tao Liu, Yiwen Liang, Xiaodie Wang, Meiqi Shao, Congcong Wang, Jianchen Yu, Yan Sun, Pingjing Zhang, Qijun Qian
This paper designs a 5' UTR that enables rapid, cost-effective analysis of mRNA capping efficiency and poly(A) tail length without probes or biotin.
bioRxiv · Oct 10, 2026 · PreprintBioengineering