GenomicsbioRxivPreprint
An Engineered Halotolerant Chimeric T7 RNA Polymerase for High-Yield, Low-Immunogenicity Synthesis of RNA via Simple Batch Transcription
Yuan Fang, Yan Sun, Congcong Wang…·Pingjing Zhang
This paper introduces a halotolerant chimeric T7 RNA polymerase that improves RNA synthesis yield, reduces immunogenicity, and enhances transcript quality under high-salt conditions.
DOI 10.64898/2026.05.13.724829