Orc6 at replication fork enables efficient mismatch repair
Yo-Chuen Lin, Arindam Chakraborty, Dazhen Liu, Jaba Mitra, Lyudmila Y. Kadyrova, Rosaline Y.C. Hsu, Mariam K. Arif, Sneha Adusumilli, Taekjip Ha, Farid A. Kadyrov, Kannanganattu V. Prasanth, Supriya G. Prasanth
This paper identifies hOrc6's role in promoting S-phase progression by facilitating mismatch repair complex assembly and activity at the replication fork.
bioRxiv · May 10, 2021 · PreprintMolecular Biology