A genetic screen in enteroendocrine cells reveals mechanisms that control protein sensing and GLP-1 release
Shenliang Yu, Yoochae Lee, Steven C. Boggess, Nicole R Klein, Noam Teyssier, Martin Kampmann, Zachary A. Knight
This study identifies mitochondrial respiration genes as critical for protein sensing and GLP-1 release in enteroendocrine cells through a CRISPR screen.
bioRxiv · Jan 6, 2026 · PreprintPhysiology