Chk2 sustains PLK1 activity in mitosis to ensure proper chromosome segregation
Elizabeth M. Black, Carlos Andrés Ramírez Parrado, Isabelle Trier, Wenxue Li, Yoon Ki Joo, Jennifer Pichurin, Yansheng Liu, Lilian Kabeche
This study identifies Chk2 as a regulator of PLK1 activity during mitosis, showing its role in preventing chromosome segregation errors and genome instability.
Nature Communications · Dec 30, 2024Peer-reviewedCell Biology