Author

Youfen Xu

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Angélique BordeyiD· 2 shared Lena H. NguyeniD· 2 shared Anne E. AndersoniD· 1 shared Heather A. BorniD· 1 shared Longbo ZhangiD· 1 shared Maanasi Nair· 1 shared Tiffany V. Lin· 1 shared Travorn Mahadeo· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 23 mutual co-author links

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2 shared papersNeuroscience

Angélique BordeyORCID

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2 papers

Recent·Most cited

The mTOR pathway genes mTOR, Rheb, Depdc5, Pten, and Tsc1 have convergent and divergent impacts on cortical neuron development and function

Lena H. Nguyen, Youfen Xu, Maanasi Nair, Angélique Bordey

This study investigates how mutations in mTOR pathway genes affect cortical neuron development and function, finding shared and distinct impacts on synaptic activity.

bioRxiv · Aug 11, 2023 · PreprintNeuroscience

Genetic expression of 4E-BP1 in juvenile mice alleviates mTOR-induced neuronal dysfunction and epilepsy

Lena H. Nguyen, Youfen Xu, Travorn Mahadeo, Longbo Zhang, Tiffany V. Lin, Heather A. Born, Anne E. Anderson, Angélique Bordey

This study shows that increasing 4E-BP1 activity in juvenile mice with FMCD reduces neuronal dysfunction and seizures by correcting electrophysiological and structural abnormalities.

Brain · Oct 15, 2021Peer-reviewedNeuroscience