Tolerance to Lung Infection in TWIK2 K+ Efflux Mediated Macrophage Trained Immunity
Josh Thompson, Yufan Li, Yuanling Song, Mohammad Anas, Jaewon Cho, Ki-Wook Kim, Asrar B. Malik, Jingsong Xu
This paper identifies ATP-mediated TWIK2 channel activation in alveolar macrophages as a mechanism for trained immunity and enhanced microbial killing.
bioRxiv · May 25, 2025 · PreprintImmunology