Author

Yuhki Saito

Howard Hughes Medical Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:mouse· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Robert B. DarnelliD· 3 shared Yuan YuaniD· 2 shared Andrew Darnell· 1 shared Chaolin ZhangiD· 1 shared Daphne A. Cooper· 1 shared David Knupp· 1 shared Donny D. LicatalosiiD· 1 shared Elisabeth A. Murphy· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersNeuroscience

Robert B. DarnellORCID

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3 papers

Recent·Most cited

NOVA2 regulates neural circRNA biogenesis

David Knupp, Daphne A. Cooper, Yuhki Saito, Robert B. Darnell, Pedro Miura

The paper identifies NOVA2 as a key regulator of circRNA biogenesis in the developing mouse brain, showing its role in enhancing circRNA levels through specific binding sites.

Nucleic Acids Research · Jun 10, 2021Peer-reviewedGenomics

Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons

Yuan Yuan, Shirley Xie, Jennifer Cordes Darnell, Andrew Darnell, Yuhki Saito, Hemali P. Phatnani, Elisabeth A. Murphy, Chaolin Zhang, Tom Maniatis, Robert B. Darnell

The paper develops a method to study cell-type specific RNA regulation in motoneurons and finds NOVA regulates cytoskeleton interactions by promoting a specific isoform of Septin 8.

Genome biology · Aug 15, 2018Peer-reviewedNeuroscience

Neuron-specific cTag-CLIP reveals cell-specific diversity of functional RNA regulation in the brain

Yuhki Saito, Yuan Yuan, Ilana Zucker-Scharff, John J. Fak, Yoko Tajima, Donny D. Licatalosi, Robert B. Darnell

The paper uses NOVA2 cTag-CLIP to study RNA regulation in specific neurons, revealing cell-type differences in RBP actions and their impact on RNA diversity and function.

bioRxiv · Jan 8, 2018 · PreprintNeuroscience