Author

Yun Shen

Harvard University

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Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:matrix factorization· 1 Assay:protein sequence· 1

Frequent Co-Authors

Alice DesbuleuxiD· 2 shared Anupama YadaviD· 2 shared Atina G. CotéiD· 2 shared Benoît CharloteauxiD· 2 shared Carles PonsiD· 2 shared Dae‐Kyum KimiD· 2 shared David De RidderiD· 2 shared DAVID EDWIN HILLiD· 2 shared

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2019-2021 · peak 1/yr

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2 shared papersSystems Biology

Alice DesbuleuxORCID

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2 papers

Recent·Most cited

Binary Interactome Models of Inner- Versus Outer-Complexome Organization

Luke Lambourne, Anupama Yadav, Yang Wang, Alice Desbuleux, Dae‐Kyum Kim, Tiziana M. Cafarelli, Carles Pons, István A. Kovács, Noor Jailkhani, Sadie Schlabach, David De Ridder, Katja Luck, Wenting Bian, Yun Shen, Zhipeng Yang, , Marc Vidal

The paper constructs a high-quality yeast binary interactome map and compares inner- and outer-complexome organization, finding the outer-complexome contains more interactions and exhibits higher functional heterogeneity.

bioRxiv · Mar 16, 2021 · PreprintSystems Biology

A reference map of the human protein interactome

Katja Luck, Dae‐Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana M. Cafarelli, Francisco Jose Campos-Laborie, Benoît Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven J. Deimling, Alice Desbuleux, , Michael A. Calderwood

The paper presents HuRI, a comprehensive human protein-protein interaction map, and demonstrates its utility in understanding cellular function and disease mechanisms.

bioRxiv · Apr 19, 2019 · PreprintSystems Biology