Author

Alice Desbuleux

Harvard UniversityORCID 0000-0002-7058-4553Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:protein structure· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Benoît CharloteauxiD· 3 shared DAVID EDWIN HILLiD· 3 shared Jean‐Claude TwizereiD· 3 shared Marc VidaliD· 3 shared Michael A. CalderwoodiD· 3 shared Anupama YadaviD· 2 shared Atina G. CotéiD· 2 shared Carles PonsiD· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSystems Biology

Benoît CharloteauxORCID

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3 papers

Recent·Most cited

The viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape

Charlotte Vandermeulen, Tina M. O’Grady, Jérôme Wayet, Bartimée Galvan, Sibusiso B. Maseko, Majid Cherkaoui, Alice Desbuleux, Georges Coppin, Julien Olivet, Lamya Ben Ameur, Keisuke Kataoka, Seishi Ogawa, Olivier Hermine, Ambroise Marçais, Marc Thiry, , Jean‐Claude Twizere

This study shows that Tax and HBZ, viral oncoproteins, alter mRNA splicing in T-cells by interacting with spliceosome components, leading to changes in cancer-related genes.

PLoS Pathogens · Sep 20, 2021Peer-reviewedSystems Biology

Binary Interactome Models of Inner- Versus Outer-Complexome Organization

Luke Lambourne, Anupama Yadav, Yang Wang, Alice Desbuleux, Dae‐Kyum Kim, Tiziana M. Cafarelli, Carles Pons, István A. Kovács, Noor Jailkhani, Sadie Schlabach, David De Ridder, Katja Luck, Wenting Bian, Yun Shen, Zhipeng Yang, , Marc Vidal

The paper constructs a high-quality yeast binary interactome map and compares inner- and outer-complexome organization, finding the outer-complexome contains more interactions and exhibits higher functional heterogeneity.

bioRxiv · Mar 16, 2021 · PreprintSystems Biology

A reference map of the human protein interactome

Katja Luck, Dae‐Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana M. Cafarelli, Francisco Jose Campos-Laborie, Benoît Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven J. Deimling, Alice Desbuleux, , Michael A. Calderwood

The paper presents HuRI, a comprehensive human protein-protein interaction map, and demonstrates its utility in understanding cellular function and disease mechanisms.

bioRxiv · Apr 19, 2019 · PreprintSystems Biology