Treatment with IFB-088 improves neuropathy in CMT1A and CMT1B mice
Yunhong Bai, Caroline Treins, Vera G. Volpi, Cristina Scapin, Cinzia Ferri, R Mastrangelo, Thierry Touvier, Francesca Florio, Francesca Bianchi, Ubaldo Del Carro, Frank Baas, David Wang, Pierre Miniou, Philippe Guédat, Michael E. Shy, Maurizio D’Antonio
This study shows that IFB-088 treatment improves neuropathy in two mouse models of CMT1B and CMT1A by reducing ER-stress and enhancing protein homeostasis.
Molecular Neurobiology · Apr 30, 2022Peer-reviewedNeuroscience